04 People

People

Daniel Fisch in the laboratory
Group Leader · Principal Investigator

Daniel Fisch

I study how innate immune cells sense danger and decide how to respond. I opened the Innate Immune Cell Biology Laboratory at GIMM in October 2026.

I trained in Molecular Medicine and Biochemistry at the University of Freiburg, with research in cell death signaling in Freiburg and at St. Jude Children's Research Hospital. For my PhD with Eva-Maria Frickel at the Francis Crick Institute and Imperial College London, I uncovered new functions of human guanylate-binding proteins in infection and cell death, and built HRMAn, an AI platform for analyzing host–pathogen images.

As a postdoc with Jonathan Kagan at Boston Children's Hospital and Harvard Medical School, I redefined how myddosomes execute Toll-like receptor signaling. At GIMM I bring together both lines of work with synthetic biology approaches that engineer signaling complexes.

CAREERPath to GIMM

  1. 2026 –Group Leader, Innate Immune Cell Biology LaboratoryGulbenkian Institute for Molecular Medicine (GIMM), Oeiras, Portugal
  2. 2022 – 2026Postdoctoral fellow with Jonathan KaganBoston Children's Hospital and Harvard Medical School, Boston, USA
  3. 2016 – 2021PhD and bridging postdoc with Eva-Maria FrickelFrancis Crick Institute, Imperial College London and University of Birmingham, UK
  4. 2014 – 2016MSc Biochemistry and BiophysicsUniversity of Freiburg, Germany
  5. 2011 – 2014BSc Molecular MedicineUniversity of Freiburg, Germany

SUPPORTFellowships and awards

  • 2027 – 2028FCT Exploratory Research Project (PEX)
  • 2027 – 2029FCT CEEC Individual, Assistant Researcher
  • 2025 – 2026HRIA Charles A. King Trust Postdoctoral Research Fellowship
  • 2022 – 2025Human Frontier Science Program (HFSP) Long-Term Fellowship
  • 2022 – 2024EMBO Postdoctoral Fellowship
  • 2017 – 2019Boehringer Ingelheim Fonds PhD Fellowship

OFF THE BENCHOutside the lab

I like understanding how things work, and that goes well beyond the lab: weather, aircraft, and anything I can take apart and fix. I hike, travel and garden whenever I get the chance, and I trained as a lifeguard and a glider pilot.

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